Is the new COVID at-home test dangerous?

Is the new Covid-19 test dangerous?

The test is self-administered, there is no doctor, nurse, or technician present. What could possibly go wrong, as millions of people perform the test on themselves?

The document below references an undated FDA document titled,

“BinaxNOWTM COVID-19 Antigen Self TEST.”

The Binax test kit is manufactured by Abbott.

Here is the key quote from the FDA: “The Reagent Solution [included in the test kit] contains a harmful chemical (see table below). If the solution contacts the skin or eye, flush with copious amounts of water. If irritation persists, seek medical advice…”

 

 

 

Then the FDA document lists that harmful chemical: sodium azide. So just how harmful is it? The following information is sourced from the CDC website.

 

What sodium azide is

  • Sodium azide is a rapidly acting, potentially deadly chemical that exists as an odorless white solid.
  • When it is mixed with water or an acid, sodium azide changes rapidly to a toxic gas with a pungent (sharp) odor. It also changes into a toxic gas (hydrazoic acid) when it comes in contact with solid metals (for example, when it is poured into a drain pipe containing lead or copper).
  • The odor of the gas may not be sharp enough, however, to give people sufficient warning of the danger.

Where sodium azide is found and how it is used

  • Sodium azide is best known as the chemical found in automobile airbags. An electrical charge triggered by automobile impact causes sodium azide to explode and convert to nitrogen gas inside the airbag.
  • Sodium azide is used as a chemical preservative in hospitals and laboratories. Accidents have occurred in these settings. In one case, sodium azide was poured into a drain, where it exploded and the toxic gas was inhaled (breathed in).
  • Sodium azide is used in agriculture (farming) for pest control.
  • Sodium azide is also used in detonators and other explosives.

How you could be exposed to sodium azide

  • Following release of sodium azide into water, you could be exposed to sodium azide by drinking the contaminated water.
  • Following contamination of food with sodium azide, you could be exposed to sodium azide by eating the contaminated food.
  • Following release of sodium azide into the air, you could be exposed by breathing in the dust or the gas that is formed.
  • Sodium azide can also enter the body and cause symptoms through skin contact.
  • An explosion involving sodium azide may cause burn injury as well as expose people to the toxic gas, hydrozoic acid.

How sodium azide works

  • The seriousness of poisoning caused by sodium azide depends on the amount, route, and length of time of exposure, as well as the age and preexisting medical condition of the person exposed.
  • Breathing the gas that is formed from sodium azide causes the most harm, but ingesting (swallowing) sodium azide can be toxic as well.
  • The gas formed from sodium azide is most dangerous in enclosed places where the gas will be trapped. The toxic gas quickly disperses in open spaces, making it less harmful outdoors.
  • The gas formed from sodium azide is less dense (lighter) than air, so it will rise.
  • Sodium azide prevents the cells of the body from using oxygen. When this happens, the cells die.
  • Sodium azide is more harmful to the heart and the brain than to other organs, because the heart and the brain use a lot of oxygen.

Immediate signs and symptoms of sodium azide exposure

  • People exposed to a small amount of sodium azide by breathing it, absorbing it through their skin, or eating foods that contain it may have some or all of the following symptoms within minutes:
    • Clear drainage from the nose (gas or dust exposure)
    • Cough (gas or dust exposure)
    • Dizziness
    • Headache
    • Nausea and vomiting
    • Rapid breathing
    • Rapid heart rate
    • Red eyes (gas or dust exposure)
    • Restlessness
    • Weakness
    • Skin burns and blisters (explosion or direct skin contact)
  • Exposure to a large amount of sodium azide by any route may cause these other health effects as well:
    • Convulsions
    • Low blood pressure
    • Loss of consciousness
    • Lung injury
    • Respiratory failure leading to death
    • Slow heart rate
  • Showing these signs and symptoms does not necessarily mean that a person has been exposed to sodium azide.

What the long-term health effects may be

Survivors of serious sodium azide poisoning may have heart and brain damage.

How people can protect themselves and what they should do if they are exposed to sodium azide

  • First, get fresh air by leaving the area where the sodium azide was released. Moving to an area with fresh air is a good way to reduce the possibility of death from exposure to sodium azide.
    • If the sodium azide release was outside, move away from the area where the sodium azide was released.
    • If the sodium azide release was indoors, get out of the building.
    • If leaving the area that was exposed to sodium azide is not an option, stay as low to the ground as possible, because sodium azide fumes rise.
    • If you are near a release of sodium azide, emergency coordinators may tell you to either evacuate the area or to a  “shelter in place” inside a building to avoid being exposed to the chemical. For more information on evacuation during a chemical emergency
    • If you think you may have been exposed to sodium azide, you should remove your clothing, rapidly wash your entire body with soap and water, and get medical care as quickly as possible.
  • Removing your clothing:
    • Quickly take off clothing that may have sodium azide on it. Any clothing that has to be pulled over the head should be cut off the body instead of pulled over the head.
    • If you are helping other people remove their clothing, try to avoid touching any contaminated areas, and remove the clothing as quickly as possible.
  • Washing yourself:
    • As quickly as possible, wash any sodium azide from your skin with large amounts of soap and water. Washing with soap and water will help protect people from any chemicals on their bodies.
    • If your eyes are burning or your vision is blurred, rinse your eyes with plain water for 10 to 15 minutes. If you wear contacts, remove them and put them with the contaminated clothing. Do not put the contacts back in your eyes (even if they are not disposable contacts). If you wear eyeglasses, wash them with soap and water. You can put your eyeglasses back on after you wash them.
  • Disposing of your clothes:
    • After you have washed yourself, place your clothing inside a plastic bag. Avoid touching contaminated areas of the clothing. If you can’t avoid touching contaminated areas, or you aren’t sure where the contaminated areas are, wear rubber gloves or put the clothing in the bag using tongs, tool handles, sticks, or similar objects. Anything that touches the contaminated clothing should also be placed in the bag. If you wear contacts, put them in the plastic bag, too.
    • Seal the bag, and then seal that bag inside another plastic bag. Disposing of your clothing in this way will help protect you and other people from any chemicals that might be on your clothes.
    • When the local or state health department or emergency personnel arrive, tell them what you did with your clothes. The health department or emergency personnel will arrange for further disposal. Do not handle the plastic bags yourself.
    • If someone has ingested sodium azide, do not induce vomiting or give fluids to drink. Also, if you are sure the person has ingested sodium azide, do not attempt CPR using mouth to mouth breathing. Performing CPR on someone who has ingested sodium azide could expose you to the chemical.
    • When sodium azide is ingested, it mixes with stomach acid and forms the toxic gas, hydrozoic acid. If a person who has ingested sodium azide is vomiting, isolate and stay away from the stomach contents (vomit) to avoid exposure to the toxic gas.
    • Do not pour substances containing sodium azide (such as food, water, or vomit) in the drain, because the drain can explode and cause serious harm.
  • Seek medical attention right away.

How sodium azide poisoning is treated

Sodium azide poisoning is treated with supportive medical care in a hospital setting. No specific antidote exists for sodium azide poisoning. The most important thing is for victims to seek medical treatment as soon as possible.

 

Sodium Azide Poisoning

TOXIC SYNDROME DESCRIPTION

The purpose of this document is to help health care workers and public health officials to recognize an unknown or suspected exposure to sodium azide. Sodium azide is a rapidly acting, potentially lethal chemical that exists as an odorless, white crystalline solid. It is used in automobile airbags to produce inflation of the airbag upon impact; after deployment, sodium azide is converted to nitrogen gas. Sodium azide is converted rapidly into hydrazoic acid vapor upon contact with water or an acid. Like sodium azide, hydrozoic acid is highly explosive. Similar to cyanide, sodium azide and hydrozoic acid also interfere with cellular respiration and aerobic metabolism, preventing the cells from using oxygen. The central nervous system and the cardiovascular system are most sensitive to acute sodium azide poisoning.

The amount and route of the exposure to sodium azide and the premorbid condition of the exposed person will contribute to the time of onset, duration, and the severity of illness.

Signs and symptoms of exposure

Following is a list of signs and symptoms that may be encountered in a person exposed to sodium azide. Signs and symptoms are not listed in order of importance, presentation or specificity. Also, partial presentations (an absence of some of the following signs/symptoms) do not necessarily imply less severe disease.

Central nervous system signs and symptoms

  • Agitation
  • Coma
  • Convulsions
  • Dizziness
  • Headache
  • Loss of consciousness (sudden collapse)

Respiratory signs and symptoms

  • Bradypnea (decreased respiratory rate)
  • Chest pain
  • Dyspnea (shortness of breath)
  • Hyperpnea (increased respiratory rate/depth)

Cardiovascular signs and symptoms

  • Bradycardia (decreased heart rate)— late
  • Flushing
  • Hypertension (high blood pressure)— early
  • Hypotension (low blood pressure)— late
  • Tachycardia (increased heart rate)— early

Gastrointestinal signs and symptoms

  • Abdominal pain
  • Nausea
  • Vomiting

Other signs

  • Similar color of retinal arteries and veins
  • Skin and eye irritation

Laboratory findings suggestive of sodium azide poisoning

  • Metabolic acidosis
  • Elevated anion gap
  • Increased plasma lactate concentration

Differential diagnosis – poisoning with

  • Carbon monoxide
  • Cyanide
  • Ethylene glycol
  • Fluoroacetate
  • Hydrogen sulfide
  • Methanol
  • Phosphine

Note: The actual clinical manifestations of an exposure to sodium azide may be more variable than the syndrome described in this document.

The FDA document quoted contains the following: “The BinaxNOW COVID-19 Antigen Self Test does not differentiate between SARS-CoV and SARS…CoV-2.”

So a positive test, indicating infection, could mean nothing more than infection with the 2003 “SARS virus”.

“Positive results do not rule out bacterial infection or co-infection with other viruses. The agent detected may not be the definite cause of disease.”

 

20 pages.

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Thanks to Alan!


 

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